Orbit

 陳月枝
專任師資,分析化學,生物科技
姓名 陳月枝
電子郵件 yuchie@mail.nctu.edu.tw
聯絡電話 (03)51-31527
網站 https://ycclab2018.wixsite.com/ycclab
實驗室電話 03-5712121#56521
職稱 教授
研究專長 分析化學, 質譜分析, 奈米生醫技術

我們實驗室主要是以分析化學及奈米生醫技術的研發為主要發展目標,尤其致力於新穎大氣壓游離質譜方法的開發,以創意發展全方位游離方法,並可針對不同極性的氣、液及固態等不同樣品直接進行質譜分析。除此之外,我們也研究合成不同特性的奈米粒子應用於新穎分析方法的開發,可針對有機分子、生物分子及微生物、細胞進行快速感測及分析。並且,我們也致力開發可針對抗藥性細菌具有辨識及毒殺效果的奈米抗生素。

實驗室的設備齊全,提供有志於分析化學及奈米生醫技術的學生良好的研究環境及紮實的研究訓練。實驗室的儀器包括各型的生物質譜儀、液相分離系統及各式各樣的分析級光譜儀,並備有一間細胞培養室及一間微生物培養室,除了紮實的分析化學訓練之外也可在實驗室學習基本生物分析技術。歡迎有興趣的學生來實驗室參觀並加入我們的研究團隊。
年度 論文名稱
2018 Ching-Yi Wu and Yu-Chie Chen*, Riboflavin Immobilized Fe3O4 magnetic nanoparticles carried with n-butylidenephthalide as targeting-based anticancer agents. , Artif. Cells Nanomed. Biotechnol., accepted. , (SCI)
2018 Te-Yu Chen, Min-Li Wu, Yu-Chie Chen* , Ultrasonication-assisted spray ionization-based micro-reactors for on-line monitoring of fast chemical reactions by mass spectrometry. , J. Mass Spectrom. , doi.org/10.1002/jms.4307., (SCI)
2018 Sin-Ge Wnag,& Yen-Chun Chen,& Yu-Chie Chen* (&contributed equally to this work)., Sin-Ge Wnag,& Yen-Chun Chen,& Yu-Chie Chen* Antibacterial gold nanoparticle-based photothermal killing of vancomycin-resistant bacteria. Nanomedicine, Nanomedicine, 13, pp1405-1416, (SCI)
2018 Ching-Yi Wu, Min-Li Wu, Yu-Chie Chen* , Selective extraction of n-butylidenephthalide from Angelica sinensis (Danggui) by using functionalized iron oxide magnetic nanoparticles as trapping probes. , Anal. Methods., 10, pp1593-1601, (SCI)
2018 Chun-Hsien Li, Yi-Ling Bai, Yu-Chie Chen* , Inhibition of the lethality of Shiga-like toxin-1 by functional gold nanoparticles., Artif. Cells Nanomed. Biotechnol. , DOI: 10.1080/21691401.2018.1438449. , (SCI)
2018 Mirza Muhammad Baig,Yu-Chie Chen* , Gold nanoparticle-based colorimetric sensing of dipicolinic acid from complex samples. , Anal. Bioanal. Chem. , 410, pp1805-1815, (SCI)
2018 Jia-Lin Wei and Yu-Chie Chen* , Using magnetic ions to probe and induce magnetism of pyrophosphates, bacteria, and mammalian cells. , ACS Appl. Mater. Inter., 10, pp30837-30843, (SCI)
2018 Karuppuchamy Selvaprakash, Yu-Chie Chen*, Functionalized gold nanoparticles as affinity nanoprobes for multiple lectins, Colloids Surf. B Biointerfaces. , 162, pp60-68, (SCI)
2018 Min-Li Wu,& Te-Yu Chen,& Wen-Jie Chen, Mirza Muhammad Fahad Baig, Yi-Cheng Wu, Yu-Chie Chen* (& the authors contributed equally to this work)., Carbon fiber ionization mass spectrometry coupled with solid phase microextraction for analysis of benzo[a]pyrene. , Anal. Chim. Acta. , DOI: 10.1016/j.aca.2018.10.037, (SCI)
2014 Microfluidic Chip Coupled with Thermal Desorption Atmospheric Pressure Ionization Mass Spectrometry. , Mass Spectrometry (Tokyo), (Others)
2014 Synthesis of Oligomeric Mannosides and Their Structure-binding Relationship Study with Concanavalin A. , Chem-Asian J., (SCI)
2014 Using Protein-Encapsulated Gold Nanoclusters as Photoluminescent Sensing Probes for Biomolecules., Biosens. & Bioelectron. , (SCI)
2014 Droplet-based Electrospray Ionization Mass Spectrometry for Qualitative and Quantitative Analysis. , J. Mass Spectrom. , pp432-436, (SCI)
2014 Automated System for Extraction and Instantaneous Analysis of Millimeter-Sized Samples. , RSC. Adv., 4, pp 10693-10701, (SCI)
2013 Nanomaterials for Photohyperthermia: A Review. , Curr. Pharm. Des., 19, pp6622-6634, (SCI)
2013 Liquid-Phase and Gas-Phase Investigation of Biomolecules in a Single Experiment. , 5, pp5908-5911, (SCI)
2013 Lysozyme-encapsulated Gold Nanocluster-based Affinity Mass Spectrometry for Pathogenic Bacteria., 27, pp2143-2148, (SCI)
2013 Automatic Sampling and Analysis of Organics and Biomolecules by Capillary Action-Supported Contactless Atmospheric Pressure Ionization Mass Spectrometry , PLoS One , 8, 6, ppe66292-, (SCI)
2013 Coffee-Ring Effects in Laser Desorption/Ionization Mass Spectrometry. , Anal. Chim. Acta., 766, pp77-82, (SCI)
2013 Time-Resolved Mass Spectrometry., TRAC-Trend Anal. Chem., 44, pp106-120, (SCI)
2013 Photoluminescent Gold Nanoclusters as Sensing Probes for Uropathogenic Escherichia coli. , PLoS One, ppe58064-, (SCI)
2013 Magnetic Nanoparticle-based Platform for Rapid Characterization of Histidine-rich Proteins and Peptides, Anal. Chem. , 85, pp3347-3354, (SCI)
2013 Hybrid Nanoparticle Matrix for Mass Spectrometry, RSC Adv. , 3, pp6865-6870, (SCI)
2012 Study of salt effects in ultrasonication-assisted spray ionization mass spectrometry, J. Mass Spectrom., 47, pp480-483, (SCI)
2012 Online monitoring of chemical reactions by contactless atmospheric pressure ionization mass spectrometry.., J. Mass Spectrom. , 47, pp586-590, (SCI)
2012 On-target labeling of intracellular metabolites combined with chemical mapping of individual hyphae revealing cytoplasmic relocation of isotopologues. , Anal. Chem. , 84, pp5110-516, (SCI)
2012 Using Gold Nanoclusters as Selective Luminescent Probes for Phosphate-containing Metabolites. , Anal. Chem., 84, pp5484-5488, (SCI)
2012 Human Serum Albumin Stabilized Gold Nanoclusters as Selective Luminescent Probes for Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus. Anal. Chem. 2012, 84, 8952-8956., Anal. Chem. , 84, pp8952-8956, (SCI)
2012 Isotope Label-aided Mass Spectrometry Reveals the Influence of Environmental Factors on Metabolism in Single Eggs of Fruit Fly., PLoS One. , 7, ppe50258-, (SCI)
2012 Recording Temporal Characteristics of Convection Currents by Continuous and Segmented-Flow Sampling., RSC Adv., 2, pp12431-12437, (SCI)
2012 Syringe Infusion-based Contactless Atmospheric Pressure Ionization Mass Spectrometry for Small and Large Biomolecules. , Mass Spectrom. Lett., 3, pp87-92, (SCI)
國家 學校名稱 系所 學位
美國 蒙大拿州立大學 化學與生化系 博士
台灣 中山大學 化學所 碩士
台灣 成功大學 化學系 學士
服務機關名稱 單位 職務 期間
瑞士蘇黎士聯邦理工大學 化學與生物科學系 訪問教授 0000.01 ~ 0000.01
國立交通大學 應用化學系 副教授 0000.01 ~ 0000.01
國立交通大學 應用化學系 助理教授 0000.01 ~ 0000.01
慈濟大學 毒理學研究所 副教授 0000.01 ~ 0000.01
慈濟醫學暨人文社會學院 毒理學研究所 助理教授 0000.01 ~ 0000.01
慈濟醫學院 運動員藥檢中心 助理教授 0000.01 ~ 0000.01
類別 年度 獎項名稱 頒獎單位
校外榮譽 2011 傑出青年學者獎 水木化學文教基金會
校外榮譽 2010 傑出青年研究獎 台灣質譜學會
校外榮譽 2005 吳大猷先生紀念獎 行政院國科會
校內榮譽 2005 年輕學者研究獎 國立交通大學
校內榮譽 2004 理學院院長獎 理學院
校外榮譽 2005 傑出青年化學獎章 Chemical Society Located in Taipei